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The global population is aging at an unprecedented rate, leading to a surge in neurodegenerative conditions such as Alzheimer's and vascular dementia. The scarcity of effective interventions for these diseases is partly due to the lack of accurate predictive... Read more models that can enhance drug development. The challenge is compounded by the fact that a mere 2% of pharmaceuticals successfully penetrate the central nervous system (CNS). In response to this critical need, our goal is to pioneer a novel blood-brain barrier (BBB) model that accurately represents the aged BBB. The creation of sophisticated in vitro cell models of aging offers a promising avenue to dissect the complexities of this phenomenon, providing a meticulously controlled setting to investigate the cellular and molecular transformations that accompany aging. This model will be constructed using human cells arranged in a complex three-dimensional tissue-like structure. Our analytical focus will be on the transference of drugs across the BBB, alongside intervention studies aimed at rejuvenating the BBB to a state reminiscent of its youthful functionality. You will become partof a team that is part of the Wellcome Leap project “Dynamic Resilience” focusing on predicting frailty in humans. Prof. Alexandra Stolzing is an internationally recognised expert in the ageing field and has worked within the University but also in start-ups and has experience in translating research. Dr. Sun Tao is an expert in cell models, quantitative prediction models and bioreactors.Read less
Program overview
Main Subject
Biological Sciences
Degree
PhD
Study Level
PHD
Study Mode
On Campus
The global population is aging at an unprecedented rate, leading to a surge in neurodegenerative conditions such as Alzheimer's and vascular dementia. The scarcity of effective interventions for these diseases is partly due to the lack of accurate predictive... Read more models that can enhance drug development. The challenge is compounded by the fact that a mere 2% of pharmaceuticals successfully penetrate the central nervous system (CNS). In response to this critical need, our goal is to pioneer a novel blood-brain barrier (BBB) model that accurately represents the aged BBB. The creation of sophisticated in vitro cell models of aging offers a promising avenue to dissect the complexities of this phenomenon, providing a meticulously controlled setting to investigate the cellular and molecular transformations that accompany aging. This model will be constructed using human cells arranged in a complex three-dimensional tissue-like structure. Our analytical focus will be on the transference of drugs across the BBB, alongside intervention studies aimed at rejuvenating the BBB to a state reminiscent of its youthful functionality. You will become partof a team that is part of the Wellcome Leap project “Dynamic Resilience” focusing on predicting frailty in humans. Prof. Alexandra Stolzing is an internationally recognised expert in the ageing field and has worked within the University but also in start-ups and has experience in translating research. Dr. Sun Tao is an expert in cell models, quantitative prediction models and bioreactors.Read less
Admission Requirements
3.2+
6.5+
92+
Students will normally need to hold, or expect to gain, at least a 2:1 degree (or equivalent) and ideally a Masters degree and/or relevant experience in a relevant discipline e.g. human biology/physiology, biological or biomedical science. Good team working, organisational and communication skills are essential. Experience of work with human participants, particularly older people, will be an advantage. Experience of collecting and handling samples will be desirable but training will be provided.
01 Apr 2025
3 Years
Apr
Tuition fees
Domestic
4,786
International
27,500
Scholarships
Selecting the right scholarship can be a daunting process. With countless options available, students often find themselves overwhelmed and confused. The decision can be especially stressful for those facing financial constraints or pursuing specific academic or career goals.
To help students navigate this challenging process, we recommend the following articles:
Biomarkers of Aging PhD
Loughborough University, Loughborough, United Kingdom
# 551-600QS Subject Rankings
36 monthsProgram duration
27,500 Tuition Fee/year
01 Apr, 2025Application Deadline
Program overview
Main Subject
Biological Sciences
Degree
PhD
Study Level
PHD
Study Mode
On Campus
Read more models that can enhance drug development. The challenge is compounded by the fact that a mere 2% of pharmaceuticals successfully penetrate the central nervous system (CNS).
In response to this critical need, our goal is to pioneer a novel blood-brain barrier (BBB) model that accurately represents the aged BBB. The creation of sophisticated in vitro cell models of aging offers a promising avenue to dissect the complexities of this phenomenon, providing a meticulously controlled setting to investigate the cellular and molecular transformations that accompany aging.
This model will be constructed using human cells arranged in a complex three-dimensional tissue-like structure. Our analytical focus will be on the transference of drugs across the BBB, alongside intervention studies aimed at rejuvenating the BBB to a state reminiscent of its youthful functionality. You will become partof a team that is part of the Wellcome Leap project “Dynamic Resilience” focusing on predicting frailty in humans.
Prof. Alexandra Stolzing is an internationally recognised expert in the ageing field and has worked within the University but also in start-ups and has experience in translating research. Dr. Sun Tao is an expert in cell models, quantitative prediction models and bioreactors. Read less
Program overview
Main Subject
Biological Sciences
Degree
PhD
Study Level
PHD
Study Mode
On Campus
Read more models that can enhance drug development. The challenge is compounded by the fact that a mere 2% of pharmaceuticals successfully penetrate the central nervous system (CNS).
In response to this critical need, our goal is to pioneer a novel blood-brain barrier (BBB) model that accurately represents the aged BBB. The creation of sophisticated in vitro cell models of aging offers a promising avenue to dissect the complexities of this phenomenon, providing a meticulously controlled setting to investigate the cellular and molecular transformations that accompany aging.
This model will be constructed using human cells arranged in a complex three-dimensional tissue-like structure. Our analytical focus will be on the transference of drugs across the BBB, alongside intervention studies aimed at rejuvenating the BBB to a state reminiscent of its youthful functionality. You will become partof a team that is part of the Wellcome Leap project “Dynamic Resilience” focusing on predicting frailty in humans.
Prof. Alexandra Stolzing is an internationally recognised expert in the ageing field and has worked within the University but also in start-ups and has experience in translating research. Dr. Sun Tao is an expert in cell models, quantitative prediction models and bioreactors. Read less
Admission Requirements
Tuition fees
Domestic
International
Scholarships
Selecting the right scholarship can be a daunting process. With countless options available, students often find themselves overwhelmed and confused. The decision can be especially stressful for those facing financial constraints or pursuing specific academic or career goals.
To help students navigate this challenging process, we recommend the following articles:
How to get a full scholarship
Looking for a fully-funded scholarship to see you into university? Find out how to boost your chances of getting one.
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Find scholarships to study abroad with our lists of international scholarships – categorized by country, by subject, and by type of student.
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Get answers to all your questions about scholarship applications, including tips on how to find scholarships and chances of success.
QS subject rankings
Subject: Biological Sciences
Ranking criteria
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Biomarkers of Aging PhD
Developing Prescription Guidelines for Passive Heat Therapy PhD
Developing Prescription Guidelines for Passive Heat Therapy PhD
Does Socialised Real-Life Body Exposure Promote Body Image Positivity PhD
Does Socialised Real-Life Body Exposure Promote Body Image Positivity PhD
Energy Dissipation In Human Soft Tissue During Impacts PhD
Energy Dissipation In Human Soft Tissue During Impacts PhD
Natural Sciences (13)
Accelerated Screening and Synthesis of New Chemotherapeutic Agents for Pancreatic Cancer PhD
Accelerated Screening and Synthesis of New Chemotherapeutic Agents for Pancreatic Cancer PhD
Bespoke Organometallic Compounds for Anticancer Studies PhD
Bespoke Organometallic Compounds for Anticancer Studies PhD
Bio-based Sustainable Materials for Autonomous Thermal Management in Wearables PhD
Bio-based Sustainable Materials for Autonomous Thermal Management in Wearables PhD
Biomimmetic Catalytic Asymmetric Synthesis of the Bisorbicillinoids and Related Products PhD
Biomimmetic Catalytic Asymmetric Synthesis of the Bisorbicillinoids and Related Products PhD
Climate and Ecological Transitions Hub Studentship PhD
Climate and Ecological Transitions Hub Studentship PhD
Coherent State Methods in Spectral Asymptotics PhD
Coherent State Methods in Spectral Asymptotics PhD
Computational Modelling of Sustainable Alloys PhD
Designing Classroom Tasks To Improve Students’ Learning Of Mathematics PhD
Developing Novel Antibiofilm Coatings for Sustainable Biofilm-Free Surfaces PhD
Development of Hybrid Microcomb Sources with Topologically Protected Dark Resonances for Simultaneous Classical and Quantum PhD
Development of Novel Bicyclopentanes (BCP) Bioisosteres From Bench Stable [1.1.1]-Propellane Precursors PhD
Digital Twins for Biofilm Management PhD
Dispersionless Integrable Systems In 2+1 Dimensions PhD
Social Sciences and Management (5)
An Evaluation of Erasmus+ Sport Projects and Their Impact on EU Sport Policy Development PhD
An Evaluation of Erasmus+ Sport Projects and Their Impact on EU Sport Policy Development PhD
Climate Change, Work Design and Worker Wellbeing Phd
Climate Change, Work Design and Worker Wellbeing Phd
Communication and Social Change (CSC) Hub Studentship PhD
Communication and Social Change (CSC) Hub Studentship PhD
Enhancing Motivation in Sport and Exercise Contexts PhD
Enhancing Motivation in Sport and Exercise Contexts PhD
Out of School Youth Provision: An Analysis of Funding and Operational Resilience within the Sector PhD
Out of School Youth Provision: An Analysis of Funding and Operational Resilience within the Sector PhD