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Bespoke Organometallic Compounds for Anticancer Studies PhD
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Bespoke Organometallic Compounds for Anticancer Studies PhD
Loughborough University, Loughborough, United Kingdom
# 301-350QS Subject Rankings
36 monthsProgram duration
27,500 Tuition Fee/year
30 Sep, 2025Application Deadline
Program overview
Main Subject
Chemistry
Degree
PhD
Study Level
PHD
Study Mode
On Campus
Read more success to the diversity of ancillary ligands that can be incorporated to access libraries of organometallic compounds possessing similar structural features.
We have been interested, for many years, in studying the chemistry of various organometallic compounds based primarily on late transition metals such as ruthenium, rhodium, iridium, palladium, and platinum to name but a few. Ideal spectator ligands, complimentary to those aforementioned target metals, often include specific Group 15 donor atoms incorporating nitrogen or phosphorus centres that can firmly anchor these metal centres.
In this exciting project, we will use synthetic methodologies developed in our research group to prepare novel families of (i) New fluorescent Schiff base chelating ligands and (ii) Preorganised fluorescent diphosphane ligands with unique bridging capabilities for anchoring two organometallic metal centres. Once synthesised and characterised, these compounds will be systematically evaluated for their cytotoxic properties.
This project will provide an excellent training opportunity, for a prospective PhD candidate, in modern well-equipped laboratories with access to multinuclear NMR facilities, X-ray crystallography, fluorescence spectroscopy, elemental imaging and bio lab testing facilities. Read less
Program overview
Main Subject
Chemistry
Degree
PhD
Study Level
PHD
Study Mode
On Campus
Read more success to the diversity of ancillary ligands that can be incorporated to access libraries of organometallic compounds possessing similar structural features.
We have been interested, for many years, in studying the chemistry of various organometallic compounds based primarily on late transition metals such as ruthenium, rhodium, iridium, palladium, and platinum to name but a few. Ideal spectator ligands, complimentary to those aforementioned target metals, often include specific Group 15 donor atoms incorporating nitrogen or phosphorus centres that can firmly anchor these metal centres.
In this exciting project, we will use synthetic methodologies developed in our research group to prepare novel families of (i) New fluorescent Schiff base chelating ligands and (ii) Preorganised fluorescent diphosphane ligands with unique bridging capabilities for anchoring two organometallic metal centres. Once synthesised and characterised, these compounds will be systematically evaluated for their cytotoxic properties.
This project will provide an excellent training opportunity, for a prospective PhD candidate, in modern well-equipped laboratories with access to multinuclear NMR facilities, X-ray crystallography, fluorescence spectroscopy, elemental imaging and bio lab testing facilities. Read less
Admission Requirements
Tuition Fee
Domestic Students
International Students
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QS subject rankings
Subject: Chemistry
Ranking criteria
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Communication and Social Change (CSC) Hub Studentship PhD
Enhancing Motivation in Sport and Exercise Contexts PhD
Enhancing Motivation in Sport and Exercise Contexts PhD
Out of School Youth Provision: An Analysis of Funding and Operational Resilience within the Sector PhD
Out of School Youth Provision: An Analysis of Funding and Operational Resilience within the Sector PhD